The film has received positive to negative reviews. Rotten Tomatoes reported that the film has a 26% "rotten" rating, based on 85 reviews with an average score of 4.6/10. The consensus is that "G-Force features manic action, but fails to come up with interesting characters or an inspired plot." By contrast, Metacritic, which assigns a normalized rating out of 100 top reviews from mainstream critics, the film has received an average score of 44%, based on 17 reviews.
Roger Ebert of the Chicago Sun-Times gave the film 2.5 stars out of four, saying that "'G-Force' is a pleasant, inoffensive 3-D animated farce about a team of superspy guinea pigs who do battle with a mad billionaire who wants to conquer the earth by programming all the home appliances made by his corporation to follow his instructions. It will possibly be enjoyed by children of all ages." However, the film was the #1 film at the box office for its opening weekend, making $31,706,934 total, replacing Harry Potter and the Half-Blood Prince. As of November 29, 2009, the film has grossed $281.1 million worldwide of which $161.8 million comes from overseas.